Previous work has shown the potential of deep learning to predict renal obstruction using kidney ultrasound images. However, these image-based classifiers have been trained with the goal of single-visit inference in mind. We compare methods from video action recognition (i.e. convolutional pooling, LSTM, TSM) to adapt single-visit convolutional models to handle multiple visit inference. We demonstrate that incorporating images from a patient's past hospital visits provides only a small benefit for the prediction of obstructive hydronephrosis. Therefore, inclusion of prior ultrasounds is beneficial, but prediction based on the latest ultrasound is sufficient for patient risk stratification.
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与痴呆症相关的认知障碍(CI)在全球范围内影响超过5500万人,并且每3秒钟以一个新病例的速度迅速增长。随着临床试验反复出现的失败,早期诊断至关重要,但是在低水平和中等收入国家中,全球75%的痴呆症病例未被诊断为90%。众所周知,当前的诊断方法是复杂的,涉及对医学笔记,大量认知测试,昂贵的脑部扫描或脊柱液体测试的手动审查。与CI相关的信息经常在电子健康记录(EHR)中找到,并且可以为早期诊断提供重要线索,但是专家的手动审查是繁琐的,并且容易发生。该项目开发了一种新型的最新自动筛选管道,用于可扩展和高速发现EHR中的CI。为了了解EHR中复杂语言结构的语言环境,构建了一个8,656个序列的数据库,以训练基于注意力的深度学习自然语言处理模型以对序列进行分类。使用序列级别分类器开发了基于逻辑回归的患者级别预测模型。深度学习系统的精度达到了93%,AUC = 0.98,以识别其EHR中没有较早诊断,与痴呆有关的诊断代码或与痴呆有关的药物的患者。否则,这些患者将未被发现或检测到太晚。 EHR筛选管道已部署在Neurahealthnlp中,这是一种用于自动化和实时CI筛选的Web应用程序,只需将EHR上传到浏览器中即可。 Neurahealthnlp更便宜,更快,更容易获得,并且胜过当前的临床方法,包括基于文本的分析和机器学习方法。它使得早期诊断可在稀缺的医疗服务中可行,但可访问的互联网或蜂窝服务。
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痴呆症是一种神经退行性疾病,导致认知下降,并影响全世界超过5000万人。痴呆症是由医疗保健专业人士诊断的 - 只有患有痴呆症的四个人中只有一名诊断出来。即使制造诊断,也可能无法作为患者图表中的疾病(ICD)诊断码的结构化国际分类。与认知障碍(CI)有关的信息通常在电子健康记录(EHR)中发现,但专家临床医生票据的手工审查既耗时,往往容易出错。本票据的自动化挖掘为在EHR数据中标记有认知障碍患者的机会。我们开发了自然语言处理(NLP)工具,以识别具有认知障碍的患者,并证明语言背景提高了认知障碍分类任务的性能。我们微调我们的注意力深入学习模型,可以从复杂的语言结构中学习,并且相对于基线NLP模型的精度(0.93)大大提高(0.84)。此外,我们表明深度学习NLP可以成功识别没有痴呆相关的ICD代码或药物的痴呆症患者。
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Logic Mill is a scalable and openly accessible software system that identifies semantically similar documents within either one domain-specific corpus or multi-domain corpora. It uses advanced Natural Language Processing (NLP) techniques to generate numerical representations of documents. Currently it leverages a large pre-trained language model to generate these document representations. The system focuses on scientific publications and patent documents and contains more than 200 million documents. It is easily accessible via a simple Application Programming Interface (API) or via a web interface. Moreover, it is continuously being updated and can be extended to text corpora from other domains. We see this system as a general-purpose tool for future research applications in the social sciences and other domains.
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This paper proposes a novel observer-based controller for Vertical Take-Off and Landing (VTOL) Unmanned Aerial Vehicle (UAV) designed to directly receive measurements from a Vision-Aided Inertial Navigation System (VA-INS) and produce the required thrust and rotational torque inputs. The VA-INS is composed of a vision unit (monocular or stereo camera) and a typical low-cost 6-axis Inertial Measurement Unit (IMU) equipped with an accelerometer and a gyroscope. A major benefit of this approach is its applicability for environments where the Global Positioning System (GPS) is inaccessible. The proposed VTOL-UAV observer utilizes IMU and feature measurements to accurately estimate attitude (orientation), gyroscope bias, position, and linear velocity. Ability to use VA-INS measurements directly makes the proposed observer design more computationally efficient as it obviates the need for attitude and position reconstruction. Once the motion components are estimated, the observer-based controller is used to control the VTOL-UAV attitude, angular velocity, position, and linear velocity guiding the vehicle along the desired trajectory in six degrees of freedom (6 DoF). The closed-loop estimation and the control errors of the observer-based controller are proven to be exponentially stable starting from almost any initial condition. To achieve global and unique VTOL-UAV representation in 6 DoF, the proposed approach is posed on the Lie Group and the design in unit-quaternion is presented. Although the proposed approach is described in a continuous form, the discrete version is provided and tested. Keywords: Vision-aided inertial navigation system, unmanned aerial vehicle, vertical take-off and landing, stochastic, noise, Robotics, control systems, air mobility, observer-based controller algorithm, landmark measurement, exponential stability.
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Recent advances in upper limb prostheses have led to significant improvements in the number of movements provided by the robotic limb. However, the method for controlling multiple degrees of freedom via user-generated signals remains challenging. To address this issue, various machine learning controllers have been developed to better predict movement intent. As these controllers become more intelligent and take on more autonomy in the system, the traditional approach of representing the human-machine interface as a human controlling a tool becomes limiting. One possible approach to improve the understanding of these interfaces is to model them as collaborative, multi-agent systems through the lens of joint action. The field of joint action has been commonly applied to two human partners who are trying to work jointly together to achieve a task, such as singing or moving a table together, by effecting coordinated change in their shared environment. In this work, we compare different prosthesis controllers (proportional electromyography with sequential switching, pattern recognition, and adaptive switching) in terms of how they present the hallmarks of joint action. The results of the comparison lead to a new perspective for understanding how existing myoelectric systems relate to each other, along with recommendations for how to improve these systems by increasing the collaborative communication between each partner.
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A "heart attack" or myocardial infarction (MI), occurs when an artery supplying blood to the heart is abruptly occluded. The "gold standard" method for imaging MI is Cardiovascular Magnetic Resonance Imaging (MRI), with intravenously administered gadolinium-based contrast (late gadolinium enhancement). However, no "gold standard" fully automated method for the quantification of MI exists. In this work, we propose an end-to-end fully automatic system (MyI-Net) for the detection and quantification of MI in MRI images. This has the potential to reduce the uncertainty due to the technical variability across labs and inherent problems of the data and labels. Our system consists of four processing stages designed to maintain the flow of information across scales. First, features from raw MRI images are generated using feature extractors built on ResNet and MoblieNet architectures. This is followed by the Atrous Spatial Pyramid Pooling (ASPP) to produce spatial information at different scales to preserve more image context. High-level features from ASPP and initial low-level features are concatenated at the third stage and then passed to the fourth stage where spatial information is recovered via up-sampling to produce final image segmentation output into: i) background, ii) heart muscle, iii) blood and iv) scar areas. New models were compared with state-of-art models and manual quantification. Our models showed favorable performance in global segmentation and scar tissue detection relative to state-of-the-art work, including a four-fold better performance in matching scar pixels to contours produced by clinicians.
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Increasing popularity of deep-learning-powered applications raises the issue of vulnerability of neural networks to adversarial attacks. In other words, hardly perceptible changes in input data lead to the output error in neural network hindering their utilization in applications that involve decisions with security risks. A number of previous works have already thoroughly evaluated the most commonly used configuration - Convolutional Neural Networks (CNNs) against different types of adversarial attacks. Moreover, recent works demonstrated transferability of the some adversarial examples across different neural network models. This paper studied robustness of the new emerging models such as SpinalNet-based neural networks and Compact Convolutional Transformers (CCT) on image classification problem of CIFAR-10 dataset. Each architecture was tested against four White-box attacks and three Black-box attacks. Unlike VGG and SpinalNet models, attention-based CCT configuration demonstrated large span between strong robustness and vulnerability to adversarial examples. Eventually, the study of transferability between VGG, VGG-inspired SpinalNet and pretrained CCT 7/3x1 models was conducted. It was shown that despite high effectiveness of the attack on the certain individual model, this does not guarantee the transferability to other models.
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Spectrum coexistence is essential for next generation (NextG) systems to share the spectrum with incumbent (primary) users and meet the growing demand for bandwidth. One example is the 3.5 GHz Citizens Broadband Radio Service (CBRS) band, where the 5G and beyond communication systems need to sense the spectrum and then access the channel in an opportunistic manner when the incumbent user (e.g., radar) is not transmitting. To that end, a high-fidelity classifier based on a deep neural network is needed for low misdetection (to protect incumbent users) and low false alarm (to achieve high throughput for NextG). In a dynamic wireless environment, the classifier can only be used for a limited period of time, i.e., coherence time. A portion of this period is used for learning to collect sensing results and train a classifier, and the rest is used for transmissions. In spectrum sharing systems, there is a well-known tradeoff between the sensing time and the transmission time. While increasing the sensing time can increase the spectrum sensing accuracy, there is less time left for data transmissions. In this paper, we present a generative adversarial network (GAN) approach to generate synthetic sensing results to augment the training data for the deep learning classifier so that the sensing time can be reduced (and thus the transmission time can be increased) while keeping high accuracy of the classifier. We consider both additive white Gaussian noise (AWGN) and Rayleigh channels, and show that this GAN-based approach can significantly improve both the protection of the high-priority user and the throughput of the NextG user (more in Rayleigh channels than AWGN channels).
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Automatic Speech Recognition (ASR) systems frequently use a search-based decoding strategy aiming to find the best attainable transcript by considering multiple candidates. One prominent speech recognition decoding heuristic is beam search, which seeks the transcript with the greatest likelihood computed using the predicted distribution. While showing substantial performance gains in various tasks, beam search loses some of its effectiveness when the predicted probabilities are highly confident, i.e., the predicted distribution is massed for a single or very few classes. We show that recently proposed Self-Supervised Learning (SSL)-based ASR models tend to yield exceptionally confident predictions that may hamper beam search from truly considering a diverse set of candidates. We perform a layer analysis to reveal and visualize how predictions evolve, and propose a decoding procedure that improves the performance of fine-tuned ASR models. Our proposed approach does not require further training beyond the original fine-tuning, nor additional model parameters. In fact, we find that our proposed method requires significantly less inference computation than current approaches. We propose aggregating the top M layers, potentially leveraging useful information encoded in intermediate layers, and relaxing model confidence. We demonstrate the effectiveness of our approach by conducting an empirical study on varying amounts of labeled resources and different model sizes, showing consistent improvements in particular when applied to low-resource scenarios.
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